Journal of Neurological Sciences (Turkish) 2017 , Vol 34 , Num 3
Cortical Relay Time Shortens in Parkinson's Disease with Apraxia
Ayşegül GÜNDÜZ1,Meral E. KIZILTAN1,Hatice KUMRU2,Semra OĞUZ5,Günes KIZILTAN1,Sibel ERTAN1,Hülya APAYDIN1
1Department of Neurology, Cerrahpasa School of Medicine, Istanbul University
2Institut Guttmann, Institut Universitari de Neurorehabilitació adscrit a la UAB, Badalona, Barcelona, Spain
3Institut Guttmann, Institut Universitari de Neurorehabilitació adscrit a la UAB, Badalona, Barcelona, Spain
4Fundació Institut d\'Investigació en Ciències de la Salut Germans Trias i Pujol, Badalona, Barcelona, Spain
5Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Marmara University
DOI : 10.24165/jns.9736.16 Cortical relay time (CRT) is a neurophysiologic method that measures transmission between sensory and motor cortices. In this study, we calculated CRT to evaluate intrahemispheric transmission in idiopathic Parkinson's disease (PD). We recorded the following parameters: 1) long latency reflexes (LLRs), 2) motor-evoked potentials (MEPs), and 3) somatosensory- evoked potentials (SEPs) according to previously published reports, and cortical relay time was calculated using the following formula: Latency of LLR II - (onset latency of MEP response + latency of N20 response of SEP). CRT was shorter in patients with apraxia compared with patients without apraxia. The findings may raise the possibility of intrahemispheric aberrant conduction or abnormal synaptic reorganization in the presence of apraxia in PD. Keywords : Apraxia, Parkinson's disease, Cortical relay time