Journal of Neurological Sciences (Turkish) 2017 , Vol 34 , Num 3
The Comparison of Socio-Demographic and Clinical Variables of Inmates Using Gabapentin For Medicinal Purposes and Those Abusing The Drug
Faruk CİCEKCİ1,Dincer YUKSEKKAVAS2,Adem AYDIN3,Adnan KARAİBRAHİMOGLU4,Ali Ulvi UCA5
1Selçuk University, Medical Faculty, Anesthesiology and Reanimasion, Konya, Turkey
2Konya E Type Prison, Department of Medicine, Konya, Turkey
3Necmettin Erbakan University, Medical Faculty, Department of Psychiatry, Konya, Turkey
4Necmettin Erbakan University, Medical Faculty, Department of Medical Education and Informatics, Konya, Turkey
5Necmettin Erbakan University, Medical Faculty, Department of Nerology, Konya, Turkey
DOI : 10.24165/jns.10014.17 Objective: To compare the socio-demographic and clinical data of inmates using gabapentin for medicinal purposes and those abusing the drug.

Methods: The study included inmates of the Konya E-Type Prison who used gabapentin between June 2012 and December 2014 and were admitted to the prison polyclinic. The participants were divided into two groups; those using gabapentin due to existing symptoms without any labeled indication (Group 1), and those using the medication due to disorders with labeled indications (Group 2). Both groups were investigated in terms of drug addiction, drug abuse, and gabapentin abuse according to the Diagnostic and Statistical Manual-Text Revision (DSM IV-TR).

Results: Nearly all inmates (n=21) using gabapentin with off-label indications (Group 1) reported using it due to muscle pain, neuropathic pain, sleep disorder, signs of anxiety, sweating, trembling, and nausea-vomiting, whereas those using gabapentin with labeled indications (Group 2) reported using it because of their diseases, such as diabetic neuropathy and epilepsy. Alcohol/substance abuse was found higher among the first-degree relatives of those using gabapentin with off-label indications (P < 0.001). The rates of substance dependence (n=10) and substance abuse (n=13) were significantly higher in Group 1 than in Group 2 (P < 0.001).

Conclusion: The inmates who were diagnosed as having drug addiction and substance abuse according to the DSM-IV-TR used gabapentin after entering prison to prevent opioid withdrawal symptoms. Keywords : Gabapentin, inmates, substance abuse, substance addiction