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2010 ISSUE / SAYI #153 Editor Prof. Nezih OKTAR MD |
JNS Turk NEWSLETTER
Official Monthly Newsletter of the Journal of Neurological Sciences -Turkish |
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Scientific misconduct
declaration from Harvard
Dear Colleagues and readers,
Definition of scientific misconduct as reproduced in the COPE* report of 1999 is the violation of the standard codes of scholarly conduct and ethical behavior in professional scientific research. When we consider doing research such in an area of neuroscience subjects as cognition, behavior and even in animals is painstaking, slow, laborious, and rarely leads to unambiguous results says primatologist Frans de Waal of Emory University in Atlanta, Georgia. Evolutionary psychologist Marc Hauser's research on primate cognition has been criticized and very recently Harvard University had been investigated for scientific misconduct. Hauser studies the evolution of key human characteristics, such as morality, language and mathematical ability, by tracing the origins of these traits in non-human primates. A popular professor and mentor, his research output has been diverse and prodigious, generating about one peer-reviewed paper per month for the past four years and forming the basis for popular articles, books and media appearances [1].
Evolutionary psychologist Dr.Marc Hauser from Harvard Researchers close to those involved say that the Harvard investigation, launched after three of Hauser's graduate students became troubled by how he interpreted his data and reported their concerns to the university, has discovered eight instances of misconduct. Hauser, who has taken a one-year period of leave from Harvard, has not responded to requests for comment. Harvard will not discuss its investigation, but says the results have been reported to the two federal agencies that provide funding for Hauser's work. Both the National Science Foundation and the Office of Research Integrity at the National Institutes of Health, have declined to comment on the matter, but the practice in such cases is that findings are made public only if government officials conclude that a researcher has acted improperly.On the other hand Dr.Hauser has admitted only to unspecified "mistakes" not to misconduct. Many of his experiments involved inferring a monkey’s thoughts or expectations from its response to a sight or sound. But the technique required somewhat subjective assessments by the researcher as to whether the monkey stared longer than usual at a display or turned its head toward a loudspeaker broadcasting an unexpected sound. In his statement, Dr. Hauser, who is on a year-long leave, said: “I acknowledge that I made some significant mistakes and I am deeply disappointed that this has led to a retraction and two corrections. I also feel terrible about the concerns regarding the other five cases, which involved either unpublished work or studies in which the record was corrected before submission for publication.”[2] Harvard University is one of the leading in research and should clearly reveal the details of their internal investigation on this matter. Scientific misconduct is not a problem of a developing country only but in all part of the globe. We have an anonymous quote in Turkish which may translate to "The fish stinks from the head" in English.
Sincerely yours, Prof. Nezih Oktar M.D.
References
*COPE = Committee on Publication Ethics
Prof. Nezih Oktar MD
................Editorial in Turkish.................................................
Harvard Üniversitesinden bilimsel kabahat açıklaması
Sevgili meslektaşlarım ve okuyucular,
Harvard Üniversitesinden Evrimsel psikolojist Dr.Marc Hauser Konuya aşina olan araştırmacıların belirttiklerine göre Hauser'in üç öğrencisi bilimsel veriler ile olan sıkıntılarını üniversite idaresine bildirmeleri sonucu 8 adet hata tesbit edilmiştir. Harvard Üniversitesinden bir yıl uzaklaştırma cezası alan Hauser o dönemde herhangi bir yorumda bulunmamıştır. Üniversite ise soruşturma sonçlarını açıklamayacaklarınu ancak iki federal makama durumu rapor ettiklerini bildirmekle yetinmişlerdir. Ulusal Bilim Kurulu ve Ulusal Sağlık Enstitüsündeki devlet görevlilerinin araştırmacının uygunsuz davranışının tesbiti halinde ancak durumu halka açıklayabileceklerini bildirmişlerdir.Öte yanda Dr. Hauser tanımlayamayacığı "hata"ları yaptığını ancak bunun kabahat olarak kabul edilemeyeceğini belirtmiştir. Çalışmalarının çoğu maymunların düşünce ve beklentilerini onların görüş ve sese yanıtları ile anlam çıkarmaya dayanmaktadır. Ancak bu teknik bir çeşit subjektif değerlendirmeleri içermekte; maymun ya beklenenden daha uzun süre bir görüntüye bakmakta ya da beklenmeyen yönden gelen sese başını çevirmektedir. Dr.Hauser "Önemli hatalar yaptığımı kabul ediyorum ve geri çekme ve iki kez düzeltme yapmam gerektiği için çok üzgünüm. Diğer üzüntü kaynağım ise beş ayrı olay için de bunların ya yayınlanmamış olması ya da yayın öncesi düzeltilmiş olmalarıdır." demiştir [2]. Harvard Üniversitesi araştırma alanında liderlerden bir tanesidir ve bu olay ile ilgili olarak iç soruşturma ayrıntılarını şeffaf bir şekilde açıklamak zorundadır. Bilimsel kabahat sadece gelişmekte olan ülkerin değil ama tüm Dünya'nın sorunudur. Bizim Türkçe'de bir deyim vardır ve İngilizce'ye de "Balık baştan kokar" diye çevrilebilir. En iyi
dileklerimle, Prof. Dr. Nezih Oktar
Kaynaklar
*COPE = Uluslararası Yayın Etiği Komisyonu
Prof. Dr. Nezih Oktar From "J Neurol Sci Turk" editorial
...............................................................................................
Harvard
probe kept under wraps p908
Sports-Related Repetitive Brain Trauma May Cause ALS-Like DiseaseAugust 18, 2010 — Scientists have increasingly linked the head injuries common in contact sports to neurodegenerative disorders, including motor neuron diseases such as amyotrophic lateral sclerosis (ALS). The link appears more convincing in light of a new study published in the September issue of the Journal of Neuropathology and Experimental Neurology. Lead author Ann McKee, MD, codirector of the Center for the Study of Traumatic Encephalopathy at Boston University, Massachusetts, and colleagues report that they have found the first pathological evidence showing that repetitive brain trauma in contact sports may be associated with motor neuron disease (MND). The evidence consisted of 2 kinds of damaged, havoc-wreaking proteins in the spinal cords of 3 professional athletes, all of whom have been diagnosed with ALS. From "MedScape Neurology"
The Lancet is renowned the world over for publishing groundbreaking medical research. The latest Impact Factor of 30.76 is our best yet - and we endeavour to build on this reputation every day by publishing world class content. Your peers recognize the value of this content and we have highlighted below the top 20 downloaded articles so far this year. All article abstracts can be viewed free of charge by clicking on the links below. *Neuroscience related articles have been selected only From "The Lancet"
Do You Want to Know How Long You
Will Live? From "MedScape"
Cholesterol Reduction and the Brain–Heart ConnectionAbstractA post hoc analysis of SPARCL data provides additional support for the benefits of statin therapy after a stroke or transient ischemic attack, in terms of both brain and cardiac protection. IntroductionResearchers previously reported a benefit from 80 mg of atorvastatin daily in preventing recurrent cerebrovascular and cardiovascular events over 5 years after a first stroke or transient ischemic attack (TIA) in the randomized, placebo-controlled, manufacturer-sponsored SPARCL trial (N Engl J Med 2006; 355:549; JW Cardiol Aug 30 2006). Now, the authors report subanalysis results. The 4731 participants had documented elevated LDL levels and stroke or TIA within the prior 6 months and no history or evidence of coronary heart disease (CHD). A handful of randomized patients were not included in the outcomes data for this report. Rates of major coronary events (MCE) or any CHD endpoint were significantly lower with atorvastatin compared with placebo: Rates of MCE were 3.4% vs. 5.1%, respectively (absolute risk reduction, 1.7%; number needed to treat [NNT], 59). Rates of any CHD event were 5.2% and 8.6%, respectively (absolute risk reduction, 3.4%; NNT, 29). During the course of the study, stroke risk decreased with time but MCE risk remained stable. The rates of MCE and any CHD were similar between patients with and without carotid disease at baseline. From "MedScape-Neurology/Neurosurgery"
'Ick' Factor
If you've ever found yourself wrist deep in peeled grapes at a Halloween party, then a new study's results won't surprise you: Researchers have found that touch and disgust can—quite literally—go hand in hand. Scientists consider disgust a universal emotion and think it probably evolved to help people avoid pathogens. Gagging at the smell of rotten eggs, for example, discourages hungry humans from eating spoiled food that could make them sick. Psychologist Debra Lieberman and colleagues at the University of Miami in Florida wondered whether the often-overlooked sense of touch could elicit that icky feeling. So the team brought the classic Halloween game into the lab: They asked 50 students to touch and rate the yuckiness of wet and dry pieces of rope and dough that were hidden out of sight in boxes. The students consistently ranked the wet items as more disgusting and found the wet dough to be the grossest of all. That's natural enough, says Lieberman, because soft, moist things have a more "biological consistency"—that is, they're more reminiscent of the wet environments in which pathogens like to live. The study, published online 20 July in Cognition & Emotion, is the first of its kind and "makes a lot of sense," says Daniel Fessler, an evolutionary anthropologist at the University of California, Los Angeles. But he notes that testing a more cross-cultural selection of disgustees would strengthen the results. "We live in a society of soap and Purell," he says. "Collegeage Americans are probably the most disgust-sensitive population in the world."
From "Science"
*ClinicalTrials.gov
Online Training
From "NLM"
To infinity and beyond: The struggle to save arithmetic
Here's an unsettling thought. The more closely mathematicians check under the hood of arithmetic, the more convinced they've become that something doesn't quite add up – and that the only way to fix it lies deep within the idea of infinity. And here's another: is DNA profiling as rock-solid as we've come to believe? Linda Geddes exposes its shortcomings in an exclusive investigation for New Scientist. Also this week: the latest on how to slake the world's thirst, why ER is in need of major surgery and a clever way to help blind people see with sound. Roger Highfield, editor, New Scientist magazine From "NewScientist"
Citizen Scientist
University of Southern California (USC) neuroscientist Roberta Diaz Brinton was among 13 people honored at the White House last week with the 2010 Presidential Citizens Medal, the nation's second highest civilian honor. Brinton, who studies how aging and neurodegenerative disease affect the neural mechanisms of cognition, was recognized for her contributions to science and technology education. "When I was a graduate student in neuropharmacology, I was one of the only females and the only student from a working-class background, and I was determined somehow to change that," Brinton says. After meeting a group of promising high school students whose classroom was a trailer in the back lot of a school in East Los Angeles, Brinton founded the USC STAR Program, which she has directed for the past 19 years. The program teaches elementary through high school students and their teachers about science and provides hands-on research opportunities in labs at USC.
From "Science"
The British Medical Journal ask for £2500 per article to pay publication fee from the author(s) The BMJ has a new policy of asking authors of eligible research articles to pay a publication fee. It only applies when the funder has already pledged to pay for open access publication and when authors can claim the BMJ fee, in full, for that specific piece of research. The move does not affect the journal’s publication policy. All submitted research will continue to be judged entirely on its importance, originality, quality, and relevance, and all research will remain openly accessible, regardless of whether a fee has been paid for its publication.From "BMJ"
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THE MICHAEL PRIZE
For the best
contribution to scientific and clinical research
which promote further
development in epileptology
Announcement for the
2011 Michael Prize
The MICHAEL PRIZE was
awarded for the first time in 1963 to stimulate epilepsy research in Germany; it is now one of the most
highly regarded international awards for the best contribution to scientific and
to clinical research which promote further development in epileptology.
The MICHAEL PRIZE is
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The prize fund is EUROS
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For the MICHAEL PRIZE
2011, up to a maximum of three papers in English language may be considered, at least one of
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The papers, together
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ULAKBİM Cahit Arf Bilgi Merkezi bünyesinde geliştirilen “Ulusal
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Saygılarımla
Dr. Elif Aytek GÜRSES
Müdür Yrd.V.
TÜBİTAK ULAKBİM
Bilkent, Ankara
Resident
Traveling Fellowship in
Pediatric Neurosurgery
The Joint Pediatric Neurosurgery Section of the American Association
of Neurological Surgeons and Congress of Neurological
Surgeons has established a traveling fellowship for residents in
accredited
North American neurosurgical training programs. The
fellowship is intended to cover the traveling and living expenses
for 1 month for a resident who wishes to gain additional experience
in pediatric neurosurgery during their residency. The
1-month fellowship can be spent at any pediatric neurosurgery
program within North America to pursue an activity which
broadens the resident’s exposure to pediatric neurosurgery,
including
observation at a clinical or research center, participation
in a research project, or any other relevant activity. Two fellowships
per year are awarded on the basis of a competitive evaluation
by a committee of the Joint Pediatric Section. The maximum fellowship
stipend is USD 2,500.
The application must include:
(1) a statement defining the purpose of the proposed fellowship;
(2) written permission from the applicant’s residency program
director
to pursue the 1-month fellowship if it is awarded;
(3) a letter of acceptance from the pediatric neurosurgical program
where the applicant will seek the fellowship;
(4) the applicant’s current CV.
The strict deadline for application submission is October 30,
2010.
The completed application should be sent to:
Bermans J. Iskandar, MD
Department of Neurological Surgery
University of Wisconsin School of Medicine and Public Health
600 Highland Avenue, Room K4/832 CSC
Madison, WI 53792 (USA)
or via e-mail to:
iskandar @ neurosurg.wisc.edu
International
Traveling Fellowship in Pediatric Neurosurgery
The Joint
Pediatric
Neurosurgery Section of the American Association
of Neurological
Surgeons
and Congress of Neurological
Surgeons has
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an international traveling fellowship for
neurosurgeons who
at the
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the annual meeting in December. The
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The application
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The strict
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The completed
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Bermans J.
Iskandar, MD
Department of
Neurological Surgery
University of
Wisconsin
School of Medicine and Public Health
600 Highland
Avenue,
Room K4/832 CSC
Madison, WI 53792
(USA)
or via e-mail to:
iskandar @
neurosurg.wisc.edu
Pituitary Network Association
Dear
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Web Communications
Pituitary Network
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ENRICO
GREPPI AWARD 2010
The Italian Society for the Study of Headaches (SISC) announces the competition of the biennial Enrico Greppi Award 2010. The award will be granted to the best unpublished original paper dealing with epidemiological, genetic, pathophysiological or therapeutic aspects of headache. The prize amounts to € 10,000 and is open to researchers of all nationalities. The papers must be submitted in accordance with the editorial instructions of The Journal of Headache and Pain. The winning article will be published ex officio in The Journal of Headache and Pain within three months of the Award presentation. The remaining papers are considered as submitted to The Journal of Headache and Pain and may be published after undergoing the peer-reviewing process. The Award is endorsed by the European Headache Federation (EHF) and the winner is invited to present the paper at the European Headache and Migraine Trust International Congress 2010 (EHMTIC), to be held in Nice, France on 28–31 October 2010. Competing papers must be written in accordance with the editorial instructions of The Journal of Headache and Pain which can be found at http://springer.com/10194 . Manuscripts submitted for the Enrico Greppi Award should be sent by e-mail to the President of SISC at sisc@sisc.it no later than 28 June 2010. For further details, please contact:
Marisa Morson
SISC Secretariat, Italian Society for the Study of Headaches, Casella Postale 32 Succ. 3, 06123 Perugia PG, Italy
Tel./Fax: 075 585 5857
E-mail: sisc@sisc.it
Website: http://www.sisc.it
Epilepsy
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The Westin Chicago River North Hotel / Chicago / IL / USA WEB: http://www.epilepsyanddepressivedisorders.com/index.asp
Full
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This educational activity will be of great value to Neuroscientists, Epileptologists, Neurologists, Psychiatrists, Nurses, Psychologists, Social Workers, Child Neurologists, Neuropsychologists and other healthcare professionals who treat Epileptic and Depressive Disorders.
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World's
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MIGRAINE HEADACHES
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TURKISH BIOETHICS ASSOCIATION
TÜRKİYE BİYOETİK DERNEĞİ
Turkish Bioethics Association
is a platform where the problems arouse in the bioethics in Turkey or
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Turkish
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Ankara Üniversitesi Tıp Fakültesi Deontoloji Anabilim
Dalı,
Morfoloji Binası 2.kat, Sıhhiye-06100, Ankara
Tel: 90.312.310 3010 / 370
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www.bilimterimleri.com adresinde tüm yazarlarımızın hizmetine sunulmuştur.
Makalelerin bilime katkısının oluşabilmesi için, makalelerinizin Türkçe anahtar kelimelerinde ortak bir dil kullanılmasına lütfen özen gösteriniz.
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Editor-in-Chief (Europe)
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Action
plan in place to protect white-necked rockfowl
International workshop steps up
measures to protect a Vulnerable species.
From " EarthWatch Institute "
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NEUROSCIENCE NEWS
July 30, 2010 — The American Heart Association/American Stroke Association has released a new guideline on the management of spontaneous intracerebral hemorrhage (ICH).
ICH has long been recognized as one of the most severe forms of stroke, among the most devastating neurologic injuries, and the view of many has been that there is not much to be done for these patients, said lead study author Lewis B. Morgenstern, MD, from the University of Michigan, Ann Arbor.
"The clear message that we want to send with this guideline is that intracerebral hemorrhage is a very treatable disorder, with very guideline-concordant, aggressive critical care," Dr. Morgenstern told Medscape Medical News. "There's a lot of evidence in the guideline of things that are shown to be effective and improve outcome."
There's also a lot of evidence that if care is not aggressive, "outcome is very bad," he added. "So the hope of the writing committee is that clinicians will use this to guide their appropriate and aggressive treatment for patients who have intracerebral hemorrhage."
The guideline, which has been reviewed and the educational content affirmed by the American Academy of Neurology, as well as the American Association of Neurological Surgeons and the Congress of Neurological Surgeons, was published online July 22 and will appear in the September issue of Stroke. The guideline applies only to spontaneous ICH, not ICH subsequent to trauma.
http://www.medscape.com/viewarticle/726066?src=mpnews&spon=26&uac=117537HR
MEDSCAPE Neurology
Learning
and memory: Ageing without forgetting
The level of CREB expression and activity predicts whether long-term
memory will decline or improve with age after life-extending strategies.
Original research paper: PLoS Biol.
8,
e1000372 (2010)
Nature / The Signaling Gateway
Evaluation of novel drugs using fMRI in early-phase clinical trials: safety monitoring
A advances in functional magnetic resonance imaging (fMRI) permit the possibility of helping with dose ranging, as well as potential drug efficacy and side-effect profiles. However there are no current guidelines or standards for fMRI that meet established standards of care. Guidelines must be adopted to be used when patients are exposed to novel drugs, in particular, when immediate access to the patient is limited. When used in initial, MRI mandates certain safety standards because subjects are positioned in the magnet thereby limiting direct observation, communication or immediate access in an emergency; in testing new drugs using fMRI, we suggest that safety guidelines merit discussion and definition. This could lead to the adoption of standards. Some of these issues are unique to the application of the technology in early-phase trials.
Edward George1,2 , Lino Becerra 1,3,4 , Jaymin Upadhyay1 , Ulrich Schmidt2 and David Borsook3,4
1 P.A.I.N. Group, Harvard Medical School, c/o Brain Imaging Center, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
2 Department of Anesthesia, Harvard Medical School, c/o Brain Imaging Center, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
3 Department of Psychiatry (Mclean and Massachusetts General Hospital), Harvard Medical School, c/o Brain Imaging Center, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
4 Department of Radiology (Massachusetts General Hospital), Harvard Medical School, c/o Brain Imaging Center, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
Drug Discovery Today, August 2010
As our Accelerating Science video explains, the August release of SciVerse will:
Over subsequent releases, SciVerse will:
For the complete story, watch the Accelerating Science video.
Elsevier EMEA Team
Researchers have identified the causative mutation for Uner Tan Syndrome, a rare and debilitating disease.
Madison, Wisconsin - July 29, 2010
A team of researchers from leading universities in Turkey and the United States have reported that they have identified the genetic mutation responsible for the Uner Tan Syndrome (UTS) using advanced genetic capture and sequencing technologies from Roche (SIX: RO, ROG; OTCQX: RHHBY). The combined genomic technologies enabled the team of scientists to identify the causative mutation of this debilitating disease after years of mystery. The study was presented by Suleyman Gulsuner, M.D. from Bilkent University, Turkey during the European Human Genetics Conference recently held in Gothenburg, Sweden at which he was awarded the prestigious Isabelle Oberlé Award for outstanding work in the field of genetics of mental retardation.http://www.roche.com/media/media_releases/med_dia_2010-07-29.htm
Roche
Largest award of $525,000 goes to Emory University.
The Muscular Dystrophy Association has award $14.1 million in new grants to 34 research leaders. During its July meeting, the MDA board of directors unanimously approved this funding round, which will be spread across universities in Australia, Belgium, Canada, Israel, The Netherlands, the U.K., and the U.S.
Read more...Genetic Engineering & Biotechnology News
Publishers big and small are producing hundreds of free-to-read, peer-reviewed online journals that charge authors fees ranging from about $500 to $3000 per paper. The most prominent publisher, the nonprofit organization Public Library of Science (PLoS), launched its first journal in 2003. This year, PLoS is on track to make a small profit. The broader open-access campaign remains rife with controversy, however. Debates rage about whether open access is speeding scientific progress. Some argue that academic researchers already have good access to the articles they need. Critics suggest that the open-access publishing model encourages mediocre work, noting that PLoS, for example, has succeeded financially only because one of its journals collects fees on thousands of lightly reviewed papers a year. Some traditional publishers—including many scientific societies—fear that at some tipping point in the future, libraries will drop subscriptions and put journals out of business. But so far, the journals haven't shown that public-access mandates have done them harm.
Full story at http://www.sciencemag.orgScience
Does Venous Insufficiency Cause MS?
CCSVI as a cause of multiple sclerosis has been receiving a lot of press and interest. Does the evidence support angioplasty for CCSVI as an effective treatment for MS?
SELECTED
ARTICLES
ARCHIVES
OF
NEUROLOGY
ANNALS
OF NEUROLOGY
Yield of systematic
transcranial doppler in patients with
transient ischemic attack
Elena Meseguer, Philippa C. Lavallée, Mikael Mazighi, Julien
Labreuche, Lucie Cabrejo, Jean-Marc Olivot, Halim Abboud, Tarik Slaoui,
Bertrand Lapergue, Céline Guidoux, Isabelle F. Klein,
Pierre-Jean Touboul, Pierre Amarenco
http://www3.interscience.
Levodopa, methylmalonic
acid, and neuropathy in idiopathic
Parkinson disease
Cory Toth, Kim Breithaupt, Shaohua Ge, Yanjun Duan, Joan M. Terris,
Anita Thiessen, Samuel Wiebe, Douglas W. Zochodne, Oksana Suchowersky
http://www3.interscience.
T2*-weighted magnetic resonance imaging with hyperoxia in acute
ischemic stroke
Krishna A. Dani, Celestine Santosh, David Brennan, Christopher McCabe,
William M. Holmes, Barrie Condon, Donald M. Hadley, I. Mhairi Macrae,
Martin Shaw, Keith W. Muir
http://www3.interscience.
Nogo-A antibodies and
training reduce muscle spasms in spinal
cord-injured rats
Roman R. Gonzenbach, Pascal Gasser, Björn Zörner, Eva
Hochreutener, Volker Dietz, Martin E. Schwab
http://www3.interscience.
Pediatric moyamoya
disease: An analysis of 410 consecutive
cases
Seung-Ki Kim, Byung-Kyu Cho, Ji Hoon Phi, Ji Yeoun Lee, Jong Hee Chae,
Ki Joong Kim, Yong-Seung Hwang, In-One Kim, Dong Soo Lee, Joongyub Lee,
Kyu-Chang Wang
http://www3.interscience.
Paraoxonase gene
mutations in amyotrophic lateral sclerosis
Nicola Ticozzi, Ashley Lyn LeClerc, Pamela J. Keagle, Jonathan D.
Glass, Anne-Marie Wills, Marka van Blitterswijk, Daryl A. Bosco,
Ildefonso Rodriguez-Leyva, Cinzia Gellera, Antonia Ratti, Franco
Taroni, Diane McKenna-Yasek, Peter C. Sapp, Vincenzo Silani, Clement E.
Furlong, Robert H. Brown Jr., John E. Landers
http://www3.interscience.
Retinal fractals and
acute lacunar stroke
Ning Cheung, Gerald Liew, Richard I. Lindley, Erica Y. Liu, Jie Jin
Wang, Peter Hand, Michelle Baker, Paul Mitchell, Tien Y. Wong,
Multi-Center Retina & Stroke Study Collaborative Group
http://www3.interscience.
NEUROLOGYBRAIN
JOURNAL
OF
NEUROLOGY NEUROSURGERY AND PSYCHIATRY
DER
NERVENARZT
>>>Non-motor Symptoms Questionnaire und Scale für das idiopathische
Parkinson-Syndrom<<<
Author(s): A. Storch, P. Odin, I. Trender-Gerhard, G. Fuchs, G. Reifschneider,
K. Ray Chaudhuri, W.H. Jost & G. Ebersbach
Page: 980 - 985
DOI: 10.1007/s00115-010-3010-z
URL: http://springer.r.delivery.net
>>>Langsam progressive Dysarthrophonie bei primärer Lateralsklerose<<<
Author(s): P.P. Urban, I. Wellach & C. Pohlmann
Page: 986 - 991
DOI: 10.1007/s00115-010-3014-8
URL: http://springer.r.delivery.net
JOURNAL
OF NEUROLOGY
>>>Progressive development of augmentation during long-term treatment with levodopa in restless legs syndrome: results of a prospective multi-center study<<<
>>>Neurologic complications in adult living donor liver transplant patients: an underestimated factor?<<<
ACTA
NEUROLOGICA SCANDINAVICA
Misdiagnosis of epileptic and non-epileptic seizures in a neurological intensive care unit (pages 189–195)
| Idiopathic
generalized epilepsies: a follow-up study in a single-center
(pages 196–201) E. Kharazmi, M. Peltola, M. Fallah, T. Ker  nen
and J. Peltola |
EUROPEAN
NEUROLOGY
EUROPEAN
JOURNAL OF NEUROLOGY
Viral meningoencephalitis: a review
of diagnostic methods and guidelines for management
I. Steiner, H. Budka, A. Chaudhuri, M. Koskiniemi, K. Sainio, O.
Salonen, P. G. E Kennedy
Abstract
Published Online: 3 Mar 2010
DOI 10.1111/j.1468-1331.2010.02970.x
EFNS guidelines on diagnosis and management of
neuromyelitis optica
J. Sellner, M. Boggild, M. Clanet, R. Q. Hintzen, Z. Illes, X.
Montalban, R. A. Du Pasquier, C. H. Polman, P. S. Sorensen, B. Hemmer
Abstract
Published Online: 7 Jun 2010
DOI 10.1111/j.1468-1331.2010.03066.x
EUROPEAN
JOURNAL OF PEDIATRIC NEUROLOGY
Developing
preschool surveillance tools for adaptive functioning: Lessons for
neuro-oncology
Pages 368-379
Michael E. Msall
Long-term
sleep disturbances in children: A cause of neuronal loss
Pages 380-390
James E. Jan, Russ J. Reiter, Martin C.O. Bax, Urs Ribary, Roger D.
Freeman, Michael B. Wasdell
Long
term clinical and electrophysiological assessment of Croatian children
with corticospinal tract involvement in Guillain–Barré
syndrome (GBS)
Pages 391-399
Nina Barišić, Lana Grković
Management
of children with nonfebrile seizures in the emergency department
Pages 439-444
Yuval E. Landau, Yehezkel Waisman, Avinoam Shuper
THE
LANCET NEUROLOGY
Cerebral
microemboli: smoking gun or innocent bystanders?
Pages 644-645
Pierre Amarenco, Elena Meseguer, Pierre-Jean Touboul
Improving
combination trials for multiple sclerosis
Pages 646-647
Maria Trojano
Gluten
sensitivity and the CNS: diagnosis and treatment
Page 653
Maurizio Versino, Federico Biagi, Paola Ilaria Bianchi, Elisabetta
Zardini, Silvia Colnaghi, Arrigo Moglia, Gino Roberto Corazza, Diego
Franciotta
Alzheimer's
disease: clinical trials and drug development
Pages 702-716
Francesca Mangialasche, Alina Solomon, Bengt Winblad, Patrizia Mecocci,
Miia Kivipelto
Recommendations
for clinical use of data on neutralising antibodies to interferon-beta
therapy in multiple sclerosis
Pages 740-750
Chris H Polman, Antonio Bertolotto, Florian Deisenhammer, Gavin
Giovannoni, Hans-Peter Hartung, Bernhard Hemmer, Joep Killestein, Henry
F McFarland, Joel Oger, Andrew R Pachner, John Petkau, Anthony T Reder,
Stephen C Reingold, Huub Schellekens, Per Soelberg Sørensen
PEDIATRIC
NEUROLOGY
Creatine
and Creatine Deficiency Syndromes: Biochemical and Clinical Aspects
Pages 163-171
Fahmi Nasrallah, Moncef Feki, Naziha Kaabachi
Correlation
Between Magnetic Resonance Imaging and Histopathologic Grades in
Rasmussen Syndrome
Pages 172-176
Sun Jun Kim, Yong D. Park, Richard Hessler, Mark R. Lee, Joseph R. Smith
Paralytic
Syndromes in Children: Epidemiology and Relationship to Vaccination
Pages 206-212
Kenneth M. Zangwill, Sylvia H. Yeh, Emily J. Wong, S. Michael Marcy,
Eileen Eriksen, Kenneth R. Huff, Martin Lee, Edwin M. Lewis, Steven B.
Black, Joel I. Ward
JOURNAL
OF CHILD NEUROLOGY
JOURNAL
OF PEDIATRIC NEUROLOGY
Serum protein S100B and nucleated red
blood cell counts
as early markers of cerebral damage in neonates with hypoxic ischemic
encephalopathy
Heba S. Elmahdy, Abed
Elrahman Elmashad, Adel A. Hagag, Sahar
Hamouda
Acute and chronic magnetic resonance imaging of human herpesvirus-6
associated encephalitis
John R. Crawford, Taeun
Chang, Bennett L. Lavenstein, Brian
Mariani
CLINICAL
NEUROLOGY AND NEUROSURGERY
Spinal meningioma:
Chronicles of
contemporary neurosurgical diagnosis and management
Pages 221-226
Christine Saraceni, James S. Harrop
&_cdi=5001&_sort=d&_docanchor=&_ct=21&_acct=C000038618&_version=1&_urlVersion=0&_userid=4410049&_fmt=full&md5=8348ad36b06a591a9e39f208d86adca2','B6T5F-4V5XP6W-1-abs','B6T5F-4V5XP6W-1-figs','B6T5F-4V5XP6W-1-refs','B6T5F-4V5XP6W-1-img','/scidirimg/preview_off.gif','/scidirimg/preview_on.gif') "Open"){kind=small}
Preview 
PDF (1774 K)
| Related
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Evaluation of brain biopsy
in the diagnosis
of severe neurologic disease of unknown etiology
Pages 235-239
Joseph D. Burns, Rebecca O. Cadigan, James A. Russell
&_cdi=5001&_sort=d&_docanchor=&_ct=21&_acct=C000038618&_version=1&_urlVersion=0&_userid=4410049&_fmt=full&md5=a418ccd72a989ff7352aad58ab248068','B6T5F-4V2J6NM-2-abs','B6T5F-4V2J6NM-2-figs','B6T5F-4V2J6NM-2-refs','B6T5F-4V2J6NM-2-img','/scidirimg/preview_off.gif','/scidirimg/preview_on.gif') "Open"){kind=small}
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PRACTICAL
NEUROLOGY
SEMINARS
IN PEDIATRIC NEUROLOGY
Volume
17, Issue 3, Pages 135-206 (September 2010)
Status Epilepticus in Children
Edited by Kevin Chapman, MD
Nonconvulsive
Status Epilepticus and Continuous Spike and Slow Wave of Sleep in
Children
Pages 155-162
Cigdem Inan Akman
REVUE
NEUROLOGIQUELocomotion et maladie de Huntington
Publication year: 2009
Source:
Revue Neurologique, In Press, Corrected Proof,
Available online 14 July 2009
A. Delval, P. Krystkowiak
BMC
NEUROLOGY
Retrospective
analysis of treatment outcome
in 315 patients with oligodendroglial brain tumors
Jan
Vesper, Erika Graf,
Johannes Tilgner, Michael Trippel, Christian Wille, Guido Nikkhah,
Christoph B Ostertag
BMC
Neurology 2009, 9:33
(16 July 2009)
[Abstract]
[Provisional
PDF] [PubMed]
[Related
articles]
The
Karachi intracranial stenosis study
(KISS) Protocol: an urban multicenter case-control investigation
reporting the clinical, radiologic and biochemical associations of
intracranial stenosis in Pakistan.
Ayeesha
Kamran Kamal, Fawad
Taj, Babar Junaidi, Asif Rasheed, Moazzam Zaidi, Muhammed Murtaza,
Naved Iqbal, Fahad Hashmat, Syed Vaqas Alam, Uzma Saleem, Shahan
Waheed, Lajpat Bansari, Nabi Shah, Maria Sameul, Madiha Yameen, Sobia
Naz, Farrukh SHAHAB Khan, Naveeduddin Ahmed, Khalid Mahmood, Niaz
Sheikh, Karim Ullah Makki, Muhammad MASROOR Ahmed, Abdul RAUF Memon,
Mohammad Wasay, Nadir ALI Syed, Bhojo Khealani, Philippe M Frossard,
Danish Saleheen
BMC
Neurology 2009, 9:31
(15 July 2009)
[Abstract]
[Provisional
PDF] [PubMed]
[Related
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NEUROLOGY
INDIA
Comparison of 1 week versus 4 weeks of
albendazole therapy in single small enhancing computed tomography lesion
[pg.560]
Prabhjeet Kaur, Praveena Dhiman, Neeraj Dhawan, Raman Nijhawan,
Sadbhavna Pandit
[ABSTRACT] [HTML
FULL TEXT] [PDF] [Mobile HTML Full text ] [EPub]
Balaji S Pai, S Muralimohan
[ABSTRACT] [HTML
FULL TEXT] [PDF] [Mobile HTML Full text ] [EPub]
Acute disseminating
encephalomyelitis with hemorrhage following dengue [pg.595]
Chanchal Gera, Uttam George
[ABSTRACT] [HTML
FULL TEXT] [PDF] [Mobile HTML Full text ] [EPub]
ACTA
NEUROLOGICA
BELGICA
Benign tremulous Parkinson’s disease
THE
EUROPEAN NEUROLOGICAL JOURNAL
OPEN NEUROLOGY
JOURNAL
NEUROSURGERY
|
Chang,
Steve W.; Abla, Adib A.; Kakarla, Udaya K.; Sauvageau, Eric; Dashti,
Shervin R.; Nakaji, Peter; Zabramski, Joseph M.; Albuquerque, Felipe
C.; McDougall, Cameron G.; Spetzler, Robert F.
|
|
Leenstra,
James L.; Tanaka, Shota; Kline, Robert W.; Brown, Paul D.; Link,
Michael J.; Nippoldt, Todd B.; Young, William F. Jr; Pollock, Bruce E.
|
JOURNAL
OF NEUROSURGERY
| The transpedicular approach compared with the anterior approach: an analysis of 80 thoracolumbar corpectomies | ||
| Daniel C. Lu, Darryl Lau, Jasmine G. Lee, and Dean Chou | ||
| Journal
of Neurosurgery: Spine Jun 2010,
Vol. 12, No. 6: 583-591. |
||
| Craniovertebral instability due to degenerative osteoarthritis of the atlantoaxial joints: analysis of the management of 108 cases | ||
| Atul Goel, Abhidha Shah, and Sanjay Rajan Gupta | ||
| Journal
of Neurosurgery: Spine Jun 2010,
Vol. 12, No. 6: 592-601. |
||
| Hirayama disease | ||
| Muh-Shi Lin, Woon-Man Kung, Wen-Ta Chiu, Rong-Kuo Lyu, Chi-Jen Chen, and Tzu-Yung Chen | ||
| Journal
of Neurosurgery: Spine Jun 2010,
Vol. 12, No. 6: 629-634. |
||
JOURNAL
OF NEUROSURGERY
Thoracolumbar
spinal
deformity: Part I. A historical passage to
1990 Historical vignette 631 Thoracolumbar
spinal
deformity: Part II. Developments from 1990 to
today Historical vignette 640 Use of pimecrolimus to prevent epidural fibrosis in a postlaminectomy rat model Laboratory investigation 758
