Demographic characteristics of patient groups with recovery or worsening after intravenous thrombolysis within 24 hours of acute ischemic stroke
İnanç Yusuf1, Arlıer Zülfikar2, Giray Semih1, inanç Yılmaz3
1Gaziantep üniversitesi tıp fakültesi, Nöroloji, Gaziantep
2Başkent üniversitesi Adana Uygulama hastanesi, Nöroloji, Adana
3Kahraman Maraş Sütcüimam Üniversitesi Tıp Fakültesi, Nöroloji, Kahramanmaraş

Background:The aim of this study was to evaluate the demographics of patients who experienced recovery or worsening after receiving intravenous thrombolytic treatment within 24 hours of the onset of acute ischemic stroke (AIS). Methods:This retrospective study included AIS patients admitted to emergency units within 4.5 hours of AIS between January 2012 and December 2015 .Recovery was defined as a decrease of ?4 points in National Institutes of Health Stroke Scale(NIHSS) score within 24 hours (Group I), and worsening was defined as an increase of ?4 points in NIHSS score within 24 hours compared to admission (Group II). Results: The study included a total of 86 patients comprising 55.8% males, with a mean (±SD) age of 61.1 (±13.1) years . The mean patient age was similar in both genders . Of the total 86 patients, 80.2% experienced recovery within 24 hours . (Group I) and symptoms worsened in 19.8% (Group II). No significant gender or age difference was determined in terms of recovery. Patients receiving thrombolysis within 1-3 hours had a higher recovery ratio compared to patients receiving treatment within 3-4.5 hours . Patients without diabetes mellitus had a better recovery ratio compared to patients with diabetes mellitus. Conclusion:A relatively high recovery rate was determined at 24 hours after thrombolysis in patients with acute ischemic stroke. Demographic characteristics were not determined to be contributing factors to this outcome, but the time to thrombolytic treatment and having diabetes mellitus were observed to be more significant predictors of patient recovery.

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